Calcium Dynamics and Cardiac Arrhythmia
نویسندگان
چکیده
منابع مشابه
Calcium Dynamics and Cardiac Arrhythmia
This Special Collection will gather all studies highlighting recent advances in theoretical and experimental studies of arrhythmia, with a specific focus on research seeking to elucidate links between calcium homeostasis in cardiac cells and organ-scale disruption of heart rhythm.
متن کاملModifying L-type calcium current kinetics: consequences for cardiac excitation and arrhythmia dynamics.
The L-type Ca current (I(Ca,L)), essential for normal cardiac function, also regulates dynamic action potential (AP) properties that promote ventricular fibrillation. Blocking I(Ca,L) can prevent ventricular fibrillation, but only at levels suppressing contractility. We speculated that, instead of blocking I(Ca,L), modifying its shape by altering kinetic features could produce equivalent anti-f...
متن کاملPlatelets and Cardiac Arrhythmia
Sudden cardiac death (SCD) remains one of the most prevalent modes of death in industrialized countries, and myocardial ischemia due to thrombotic coronary occlusion is its primary cause. The role of platelets in the occurrence of SCD extends beyond coronary flow impairment by clot formation. Here we review the substances released by platelets during clot formation and their arrhythmic properti...
متن کاملThe role of nonlinear dynamics in cardiac arrhythmia control.
The field of nonlinear dynamics has made important contributions toward a mechanistic understanding of cardiac arrhythmias. In recent years, many of these advancements have been in the area of arrhythmia control. This paper reviews the literature on analytical, modeling, and experimental nonlinear dynamical arrhythmia control with a focus on stimulation and pharmacologic techniques that have be...
متن کاملInherited Cardiac Arrhythmia Syndromes
Lethal cardiac arrhythmias in individuals with structurally normal heart are often caused by variants in genes that encode cardiac ion channel and -subunits (102). Common inherited arrhythmia syndromes include the congenital long QT syndrome (LQTS), Brugada syndrome (BrS), short QT syndrome (SQT), and catecholaminergic polymorphic ventricular tachycardia (CPVT) (76). Moreover, inherited mutatio...
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ژورنال
عنوان ژورنال: Clinical Medicine Insights: Cardiology
سال: 2017
ISSN: 1179-5468,1179-5468
DOI: 10.1177/1179546817739523